Description

Gal1-B-4Glcnac-A-Pnp is a specialized glycosyltransferase substrate and synthetic biochemical intermediate. This compound is critical for enzymatic activity studies and the synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, pharmaceutical development, and diagnostic reagent production.

Application

• Enzymatic Substrate: Used as a specific acceptor substrate for β-1,4-galactosyltransferase (GalT) enzymes in activity assays and kinetic studies.
• Glycan Synthesis: Serves as a key building block in the chemoenzymatic synthesis of N-acetyllactosamine (LacNAc) structures and more complex oligosaccharide chains.
• Bioconjugation: The para-nitrophenyl (PNP) group facilitates the creation of neoglycoconjugates for probing carbohydrate-protein interactions.
• Diagnostic Development: Employed in the research and production of diagnostic kits for detecting glycosyltransferase activity or related biomarkers.
• Inhibitor Screening: Acts as a tool compound in high-throughput screening (HTS) campaigns to identify novel glycosyltransferase inhibitors for therapeutic applications.
• Glycoengineering: Used in the development of engineered cell lines or enzymatic pathways for the production of therapeutic glycoproteins.

Basic Information

Product Name	Gal1-B-4Glcnac-A-Pnp
CAS No.	184377-56-8
Molecular Formula	C20H28N2O12
Molecular Weight	488.44 g/mol
Synonyms	p-Nitrophenyl N-Acetyl-β-D-glucosaminide; pNP-β-GlcNAc; 4-Nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranoside; N-Acetyl-β-D-glucosaminide 4-nitrophenyl; β-GlcNAc-pNP; GalT acceptor substrate; β-1,4-Galactosyltransferase acceptor; 2-Acetamido-2-deoxy-β-D-glucopyranosyl 4-nitrophenyl
EINECS	Contact for details

Quality Control

Our Gal1-B-4Glcnac-A-Pnp is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.