Description

4-Cyano-2-Isopropylaniline Hydrochloride is a high-purity, versatile organic intermediate in its stable salt form. This compound is critical for the synthesis of complex molecules, offering a reactive aniline moiety protected as a hydrochloride salt for improved handling and stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients. Its unique substitution pattern makes it a valuable building block for creating targeted chemical libraries and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the cyano and isopropyl functional groups.
• Dye and Pigment Precursor: Serves as an intermediate in the production of specialized azo dyes and high-performance pigments.
• Liquid Crystal & OLED Material Research: Employed in the development of advanced organic electronic materials due to its molecular structure and electronic properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aromatic amines.
• Chemical Research & Process Development: A valuable reagent for academic and industrial research in organic chemistry and process optimization.

Basic Information

Product Name	4-Cyano-2-Isopropylaniline Hydrochloride
CAS No.	184163-18-6
Molecular Formula	C10H13N2·HCl
Molecular Weight	196.68 g/mol (Free base: 160.22 g/mol)
Synonyms	2-Isopropyl-4-cyanoaniline hydrochloride; 4-Amino-3-isopropylbenzonitrile hydrochloride; 3-Isopropyl-4-aminobenzonitrile hydrochloride; Benzonitrile, 4-amino-3-(1-methylethyl)-, hydrochloride; 4-Cyano-2-(1-methylethyl)aniline hydrochloride; 2-(Propan-2-yl)-4-cyanoaniline hydrochloride; 4-Cyano-2-isopropyl-phenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Isopropylaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.