Description

(R)-(-)-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethyldi(3,5-Dimethylphenyl)Phosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in its ability to induce exceptional enantioselectivity and high catalytic activity in transition metal-catalyzed reactions, enabling the efficient synthesis of single-enantiomer compounds. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for developing advanced intermediates and active ingredients.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones, critical for producing chiral alcohols and amines in pharmaceutical synthesis.
• Asymmetric C-C Bond Formation: Employed in cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) and allylic substitution to construct complex, chiral molecular architectures with high fidelity.
• Pharmaceutical Intermediate Synthesis: Key catalyst component for manufacturing enantiomerically pure active pharmaceutical ingredients (APIs) and advanced chiral synthons.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is often enantiomer-specific.
• Fine Chemical and Fragrance Manufacturing: Facilitates the production of high-value chiral flavors, fragrances, and specialty chemicals.
• Academic and Industrial R&D: A vital tool for methodology development in organic synthesis and catalysis research within university and corporate laboratories.

Basic Information

Item	Details
Product Name	(R)-(-)-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethyldi(3,5-Dimethylphenyl)Phosphine
CAS No.	184095-69-0
Molecular Formula	C44H42FeP2
Molecular Weight	688.59 g/mol
Synonyms	(R)-(-)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine; Josiphos SL-J009-1; (R)-(S)-JOSIPHOS; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethylbis(3,5-dimethylphenyl)phosphine; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl-di-meta-xylylphosphine; SL-J009-1; J009-1
EINECS	Contact for details

Quality Control

Every batch of our chiral phosphine ligands is produced and tested under strict quality management protocols to ensure consistent high performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing critical parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality systems support compliance with cGMP standards for pharmaceutical applications, and specifications can be aligned with specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee, HPLC)	≥ 99.0%
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.