Description

4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Piperidine-1,4-Dicarboxylic Acid Mono-tert-Butyl Ester is a sophisticated, high-purity chemical building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the production of complex pharmaceutical molecules and bioactive compounds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in peptide chemistry and drug discovery programs, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis, particularly where the piperidine scaffold and Fmoc-protected amino functionality are required.
• Protease Inhibitor Research: Serves as a precursor in the development of protease inhibitors and other enzyme-targeting therapeutic agents.
• Chemical Biology & Bioconjugation: Employed in the design and synthesis of chemical probes, linkers, and conjugates for studying biological systems.
• Combinatorial Chemistry: A valuable scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.
• Academic & Industrial R&D: Used in research laboratories for methodological development and the synthesis of complex organic molecules.

Basic Information

Product Name	4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Piperidine-1,4-Dicarboxylic Acid Mono-tert-Butyl Ester
CAS No.	183673-66-7
Molecular Formula	C26H30N2O6
Molecular Weight	466.53 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonylamino]piperidine-4-carboxylic Acid; 4-[(Fmoc-amino)]-1-(Boc)-piperidine-4-carboxylic Acid; Fmoc-4-amino-1-Boc-piperidine-4-carboxylic Acid; 4-(Fmoc-amino)-1-Boc-piperidine-4-carboxylic Acid; 1-Boc-4-(Fmoc-amino)isonipecotic Acid; 4-[(9-Fluorenylmethoxycarbonyl)amino]-1-(tert-butoxycarbonyl)piperidine-4-carboxylic Acid; 4-(Fmoc-amino)-1-(Boc)-piperidine-4-carboxylic Acid; 4-(N-Fmoc-amino)-1-N-Boc-piperidine-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-Piperidine-1,4-Dicarboxylic Acid Mono-tert-Butyl Ester adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.