Description

3-Hydroxytetrahydrofuran-3-Carbonitrile is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structure, featuring both a hydroxyl group and a nitrile functionality on the same carbon atom within a tetrahydrofuran ring, enabling its use in constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those containing functionalized tetrahydrofuran motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of amino alcohols, lactones, and other high-value specialty chemicals.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with tailored properties.
• Academic & R&D: Employed in methodological chemistry research for studying ring-opening reactions, nucleophilic additions, and cyclization processes.

Basic Information

Product Name	3-Hydroxytetrahydrofuran-3-Carbonitrile
CAS No.	183162-37-0
Molecular Formula	C5H7NO2
Molecular Weight	113.11 g/mol
Synonyms	3-Cyano-3-hydroxytetrahydrofuran; Tetrahydro-3-hydroxy-3-furancarbonitrile; 3-Hydroxytetrahydrofuran-3-carbonitrile; 3-Hydroxyoxolane-3-carbonitrile; 3-Cyanooxolan-3-ol; 3-Hydroxy-3-tetrahydrofurancarbonitrile; 3-Hydroxy-tetrahydro-furan-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxytetrahydrofuran-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP requirements for pharmaceutical applications, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.