Description

Clenoliximab CAS NO 182912-58-9 is a chimeric monoclonal antibody designed for targeted therapeutic applications. This compound is significant for its role in modulating specific immune pathways, offering a high degree of biological specificity. It is primarily required by pharmaceutical research and development teams, as well as biopharmaceutical manufacturers, for use in preclinical studies, drug discovery, and the development of novel immunotherapies.

Application

• Primary research tool for investigating T-cell mediated immune responses and signaling pathways.
• Key reagent in the preclinical development of autoimmune disease and transplantation rejection therapies.
• Critical component in assay development for screening and validating potential immunomodulatory compounds.
• Used in pharmacokinetic and pharmacodynamic studies to understand antibody behavior in vivo.
• Reference standard for quality control and analytical method development in biopharmaceutical manufacturing.
• Essential for studying CD4 receptor interactions and their role in various disease models.

Basic Information

Product Name	Clenoliximab
CAS No.	182912-58-9
Molecular Formula	C6480H10006N1732O2040S44
Molecular Weight	~145.8 kDa
Synonyms	IDEC-151; Anti-CD4 Monoclonal Antibody (cM-T412); Chimeric Anti-CD4 Antibody; cM-T412; Immunoglobulin G1, anti-(human CD4 antigen) (human-mouse monoclonal cM-T412 γ1-chain), disulfide with human-mouse monoclonal cM-T412 κ-chain, dimer; Monoclonal Antibody cM-T412
EINECS	Contact for details

Quality Control

Our Clenoliximab is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical characterization, including assessment of purity, identity, potency, and sterility. A detailed Certificate of Analysis (COA) documenting all release specifications is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled atmospheric conditions when not in use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (SDS-PAGE)	Consistent with monoclonal antibody profile
Purity (SEC-HPLC)	≥ 95% Monomer
Protein Content (UV-A280)	≥ 1.0 mg/mL (or as specified per lot)
Biological Activity (Binding ELISA)	Conforms to reference standard
Endotoxin (LAL)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.