Description

(S)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-(4-Hydroxy-Phenyl)-Acetic Acid CAS NO 182883-41-6 is a high-purity, non-natural amino acid derivative specifically designed for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical Fmoc-protected building block, enabling the precise construction of complex peptide sequences with defined stereochemistry. It is essential for researchers and manufacturers in pharmaceutical development, bioconjugation, and the production of therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Facilitates the site-specific attachment of peptides to proteins, antibodies, or other molecules for diagnostic and therapeutic applications.
• Peptidomimetic Design: A crucial component for creating stable, bioavailable analogs of natural peptides.
• Chemical Biology Research: Employed in studying protein-protein interactions and enzyme mechanisms.
• Material Science: Potential use in creating functionalized surfaces and biomaterials.

Basic Information

Product Name	(S)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-(4-Hydroxy-Phenyl)-Acetic Acid
CAS No.	182883-41-6
Molecular Formula	C23H19NO5
Molecular Weight	389.40 g/mol
Synonyms	Fmoc-Tyr-OH; Fmoc-L-Tyrosine; Fmoc-O-benzyl-L-tyrosine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-benzyl-L-tyrosine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(4-hydroxyphenyl)propanoic Acid; N-α-Fmoc-O-benzyl-L-tyrosine; Fmoc-Tyr(Bzl)-OH; Fmoc-L-Tyrosine(Bzl)
EINECS	Contact for details

Quality Control

Our production of (S)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-(4-Hydroxy-Phenyl)-Acetic Acid adheres to stringent quality protocols suitable for research and pharmaceutical applications. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -18.0° (c=1 in DMF)
Chiral Purity	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.