Description

1-Fluoro-4-Methoxy-2-Methyl-5-Nitrobenzene is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern, featuring fluorine, methoxy, methyl, and nitro groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the nitro and fluorine groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes, pigments, and optical brighteners due to its nitro-aromatic structure.
• Liquid Crystal & OLED Materials: Acts as a building block for electronic chemicals used in display technologies.
• Academic & R&D: A valuable reagent for methodological studies in fluorination, nitration, and cross-coupling reactions within university and corporate laboratories.

Basic Information

Product Name	1-Fluoro-4-Methoxy-2-Methyl-5-Nitrobenzene
CAS No.	182880-71-3
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	2-Fluoro-5-methoxy-4-nitrotoluene; 4-Methoxy-2-methyl-1-fluoro-5-nitrobenzene; 5-Nitro-2-fluoro-4-methoxytoluene; 1-Fluoro-4-methoxy-2-methyl-5-nitro-benzene; 2-Methyl-4-methoxy-1-fluoro-5-nitrobenzene; Benzene, 1-fluoro-4-methoxy-2-methyl-5-nitro-; Toluene, 2-fluoro-5-methoxy-4-nitro-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Methoxy-2-Methyl-5-Nitrobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; store away from light.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.