Description

Gpr19 Protein CAS NO 182826-48-8 is a high-purity, biologically active protein used in advanced life science research and pharmaceutical development. This compound is critical for researchers investigating G protein-coupled receptor (GPCR) signaling pathways, drug discovery, and cellular communication mechanisms. It is an essential reagent for biotechnology companies, academic institutions, and pharmaceutical R&D laboratories focused on metabolic disorders, neurological research, and novel therapeutic target validation.

Application

• Drug Discovery & High-Throughput Screening (HTS): Used as a target protein in assays to identify and characterize novel agonists, antagonists, and modulators for therapeutic development.
• Biochemical Research: Essential for in vitro studies of GPR19 receptor structure, function, ligand binding affinity, and downstream signaling cascade analysis.
• Antibody Production & Immunoassays: Serves as a high-quality antigen for generating specific monoclonal or polyclonal antibodies for ELISA, Western Blot, and immunohistochemistry.
• Cell-Based Assays: Utilized in functional cellular assays to study receptor activation, internalization, and G-protein coupling in recombinant cell lines.
• Proteomics & Structural Biology: A key reagent for protein-protein interaction studies, crystallography trials, and mass spectrometry analysis to map interaction networks.
• Diagnostic Development: Potential use as a standard or calibrator in the development of diagnostic tests targeting GPCR-related pathways.

Basic Information

Product Name	Gpr19 Protein
CAS No.	182826-48-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GPR19; G Protein-Coupled Receptor 19; Probable G-protein coupled receptor 19; GPCR19; MGC126780; Gpr19 Protein (human, recombinant); GPR19 receptor protein
EINECS	Contact for details

Quality Control

Our Gpr19 Protein is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, confirmation of identity by mass spectrometry, and functional activity validation in cell-based assays. A detailed Certificate of Analysis (COA) documenting purity, concentration, endotoxin levels, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at ≤ -20°C in aliquots to avoid repeated freeze-thaw cycles. Use within the expiry date stated on the label. Handle using aseptic techniques appropriate for labile protein reagents.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Identification (Mass Spec)	Conforms
Protein Concentration	≥ 0.5 mg/mL
Formulation Buffer	Specified on COA
Endotoxin Level	< 1.0 EU/µg
Biological Activity (EC50)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.