Description

Carbamic Acid, (3-Amino-1-Methyl-3-Thioxopropyl)-, 1,1-Dimethylethyl Ester is a specialized thiourea derivative and a key protected intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and high-value fine chemicals. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for its utility in peptide mimetics and as a versatile building block for heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting protease inhibition or containing thiourea pharmacophores.
• Peptidomimetic Synthesis: Used to introduce thioamide or protected amino functionalities into peptide chains, modifying their stability and biological activity.
• Heterocyclic Chemistry: Serves as a precursor for the construction of various nitrogen- and sulfur-containing heterocycles, such as thiazoles and imidazolidines.
• Agrochemical Research: Employed in the development of new fungicides or herbicides where the thiocarbonyl group is essential for bioactivity.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique chemical resistance or binding properties.
• Chemical Biology Probes: Useful in creating labeled compounds or affinity probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Carbamic Acid, (3-Amino-1-Methyl-3-Thioxopropyl)-, 1,1-Dimethylethyl Ester
CAS No.	182678-75-7
Molecular Formula	C9H18N2O2S
Molecular Weight	218.32 g/mol
Synonyms	tert-Butyl (3-amino-1-methyl-3-thioxopropyl)carbamate; N-(tert-Butoxycarbonyl)-2-methyl-3-thioisoserinamide; 2-Methyl-3-[(tert-butoxycarbonyl)amino]-3-thiopropanamide; Boc-2-methyl-3-thioisoserinamide; (3-Amino-1-methyl-3-thioxopropyl)carbamic acid tert-butyl ester; tert-Butyl N-(3-amino-1-methyl-3-thioxopropyl)carbamate; 3-[(tert-Butoxycarbonyl)amino]-2-methyl-3-thiopropanamide
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Amino-1-Methyl-3-Thioxopropyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.