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2,4,6-Trifluorophenylboronic Acid CAS NO 182482-25-3


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CAS No.:182482-25-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4,6-Trifluorophenylboronic Acid is a high-purity organoboron reagent featuring a perfluorinated aromatic ring, which significantly enhances its reactivity and stability in demanding synthetic environments. This compound is a critical building block for the creation of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and reliable coupling partners for Suzuki-Miyaura cross-coupling reactions.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially fluorinated APIs where the trifluoromethyl group improves metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to enhance product efficacy and environmental persistence.
  • Material Science: Serves as a monomer or building block for creating fluorinated polymers, liquid crystals, and organic electronic materials with unique optical and electrical properties.
  • Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new catalytic processes and constructing complex molecular architectures.
  • Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 2,4,6-Trifluorophenylboronic Acid
CAS No. 182482-25-3
Molecular Formula C6H4BF3O2
Molecular Weight 175.90 g/mol
Synonyms (2,4,6-Trifluorophenyl)boronic Acid; 2,4,6-Trifluorobenzeneboronic Acid; B-(2,4,6-Trifluorophenyl)boronic Acid; 2,4,6-Trifluorophenyl-Boronic Acid; Boronic acid, B-(2,4,6-trifluorophenyl)-; 182482-25-3; 2,4,6-Trifluorophenylboronic acid (contains varying amounts of Anhydride)
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Quality Control

Our 2,4,6-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in critical applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Assay (NMR) ≥95.0%
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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