Description

Caspase-6 is a crucial cysteine-aspartic acid protease enzyme that plays a definitive role in the execution phase of apoptosis and other cellular processes. Its high purity and consistent activity are essential for reliable research and diagnostic applications in life sciences. This product is primarily utilized by researchers and developers in pharmaceutical R&D, academic biochemistry, and biotechnology for studying programmed cell death mechanisms, screening potential therapeutics, and developing assay kits.

Application

• Biochemical Research: Fundamental studies on apoptosis signaling pathways and caspase activation cascades.
• Drug Discovery & Screening: Target enzyme for high-throughput screening (HTS) of novel apoptosis modulators and therapeutic candidates.
• Diagnostic Assay Development: Key component in the development of ELISA, fluorometric, or colorimetric assay kits for caspase activity.
• Cell Biology Studies: Investigation of non-apoptotic roles of caspases in cellular differentiation, inflammation, and neuronal function.
• Pharmaceutical Quality Control: Used in activity assays to test the potency and mechanism of action of biopharmaceuticals.

Basic Information

Product Name	Caspase-6
CAS No.	182372-15-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caspase 6; Apoptotic protease Mch-2; CASP6; MCH2; Caspase-6 subunit p11; Caspase-6 subunit p18; EC 3.4.22.59
EINECS	Contact for details

Quality Control

Our Caspase-6 is produced and tested under stringent conditions to ensure high specific activity, purity, and batch-to-batch consistency. Quality assurance includes rigorous testing for enzymatic activity, purity via SDS-PAGE, and absence of contaminating proteases. A comprehensive Certificate of Analysis (COA) detailing purity, activity (units/mg), and storage buffer composition is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Conforms
Specific Activity	> XXXX units/mg protein
Purity (SDS-PAGE)	> 95%
Protein Concentration	Determined by Bradford / UV absorbance
Buffer Composition	Tris, NaCl, DTT, Glycerol, etc.
Endotoxin Level	< 1.0 EU/μg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.