Description

n-(5-Bromo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity brominated pyridine derivative, a crucial building block in advanced organic synthesis. This compound matters because it provides a reactive halogen site and a protected amide group, enabling precise molecular construction for complex target molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing advanced crop protection agents, including herbicides and fungicides with specific modes of action.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the research of organic electronic materials and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring bromo-pyridine chemistry.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions.

Basic Information

Product Name	n-(5-Bromo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	182344-63-4
Molecular Formula	C11H15BrN2O
Molecular Weight	271.16 g/mol
Synonyms	5-Bromo-N-(pyridin-2-yl)pivalamide; 2,2-Dimethyl-N-(5-bromopyridin-2-yl)propanamide; N-(5-Bromopyridin-2-yl)-2,2-dimethylpropionamide; 5-Bromo-2-pivalamidopyridine; Pivalic acid (5-bromo-2-pyridyl)amide; 182344-63-4; 5-Bromo-2-pyridylpivalamide
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.