Description

4-Fluoronaphtalene-1-Boronic Acid CAS NO 182344-25-8 is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to create novel fluorinated active ingredients with enhanced biological activity and environmental stability for crop protection.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other fluorinated functional materials for electronic and optoelectronic applications.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 4-fluoronaphthalene moiety into more complex molecular architectures in academic and industrial laboratories.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	4-Fluoronaphtalene-1-Boronic Acid
CAS No.	182344-25-8
Molecular Formula	C10H8BFO2
Molecular Weight	189.98 g/mol
Synonyms	1-Borono-4-fluoronaphthalene; (4-Fluoronaphthalen-1-yl)boronic Acid; 4-Fluoro-1-naphthaleneboronic Acid; 4-Fluoro-1-naphthylboronic Acid; 4-Fluoronaphthalene-1-boronic Acid; 4-Fluoro-1-boronaphthalene; 182344-25-8; 4-Fluoronaphthalen-1-ylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Fluoronaphtalene-1-Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.