Description

4-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through versatile cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated and trifluoromethylated biaryl scaffolds found in active pharmaceutical ingredients (APIs), leveraging the Suzuki-Miyaura cross-coupling reaction.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where the boronic acid group facilitates precise molecular assembly.
• Chemical Biology Probes: Useful in the synthesis of fluorinated probes and tags for imaging, diagnostics, and studying biological mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	182344-23-6
Molecular Formula	C7H5BF4O2
Molecular Weight	207.92 g/mol
Synonyms	[4-Fluoro-3-(trifluoromethyl)phenyl]boronic acid; (4-Fluoro-3-trifluoromethylphenyl)boronic acid; 3-Trifluoromethyl-4-fluorophenylboronic acid; 4-Fluoro-α,α,α-trifluoro-m-tolylboronic acid; Boronic acid, B-[4-fluoro-3-(trifluoromethyl)phenyl]-; 182344-23-6; 4-Fluoro-3-trifluoromethylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.