Description

2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the efficient construction of complex molecular architectures through versatile cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Functional Material Chemistry: Incorporated into specialty polymers and advanced materials to impart specific chemical and physical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Catalyst & Ligand Preparation: Used in the synthesis of sophisticated ligands and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	182344-18-9
Molecular Formula	C7H5BClF3O2
Molecular Weight	223.38 g/mol
Synonyms	[2-Chloro-5-(trifluoromethyl)phenyl]boronic acid; (2-Chloro-5-(trifluoromethyl)phenyl)boronic acid; 2-Chloro-α,α,α-trifluoro-p-tolylboronic acid; B-[2-Chloro-5-(trifluoromethyl)phenyl]boronic acid; 2-Chloro-5-trifluoromethylbenzeneboronic acid; 2-Chloro-5-trifluoromethylphenylboronic acid; 2-Chloro-5-(trifluoromethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.