Description

2Chloro5Trifluoromethoxyphenylboronicacid CAS NO 182344-18-8 is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, enabling the formation of carbon-carbon bonds under mild conditions. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its functionalized aromatic core.
• Ligand and Catalyst Preparation: Acts as a starting material for creating specialized ligands and organoboron catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	2Chloro5Trifluoromethoxyphenylboronicacid
CAS No.	182344-18-8
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.38 g/mol
Synonyms	(2-Chloro-5-(trifluoromethoxy)phenyl)boronic acid; 2-Chloro-5-(trifluoromethoxy)benzeneboronic acid; 2-Chloro-α,α,α-trifluoro-p-anisylboronic acid; B-[2-Chloro-5-(trifluoromethoxy)phenyl]boronic acid; 2-Chloro-5-trifluoromethoxybenzeneboronic Acid; 2-Chloro-5-trifluoromethoxyphenylboronic Acid; 182344-18-8; Boronic acid, B-[2-chloro-5-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 2Chloro5Trifluoromethoxyphenylboronicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.