Description

4-Fluoro-2-(Trifluoromethyl)Benzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique trifluoromethyl and fluorine substituents, which are essential for modulating the electronic and physical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules where the fluorine and trifluoromethyl groups improve lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of novel organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Benzeneboronic Acid
CAS No.	182344-16-7
Molecular Formula	C7H5BF4O2
Molecular Weight	207.92 g/mol
Synonyms	[4-Fluoro-2-(trifluoromethyl)phenyl]boronic acid; (4-Fluoro-2-(trifluoromethyl)phenyl)boronic acid; 2-Trifluoromethyl-4-fluorobenzeneboronic acid; 4-Fluoro-2-trifluoromethylbenzeneboronic acid; B-[4-Fluoro-2-(trifluoromethyl)phenyl]boronic acid; 4-Fluoro-alpha,alpha,α-trifluoro-o-tolylboronic acid; 182344-16-7
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.