Description

Cefadroxil Sulfoxide is a key pharmaceutical intermediate and oxidative impurity of the broad-spectrum cephalosporin antibiotic, Cefadroxil. Its precise synthesis and high purity are critical for ensuring the safety, efficacy, and regulatory compliance of the final active pharmaceutical ingredient (API). This compound is primarily utilized by manufacturers in the pharmaceutical industry for research, development, and quality control processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis and impurity profiling of the antibiotic Cefadroxil.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and validation.
• Impurity Standard: Essential for quality control (QC) and quality assurance (QA) to identify, quantify, and control Cefadroxil Sulfoxide as a specified impurity in Cefadroxil API and finished dosage forms.
• Research & Development: Employed in pharmacokinetic, metabolic, and stability studies related to cephalosporin antibiotics.
• Regulatory Compliance: Supports regulatory filings (e.g., FDA, EMA) by providing necessary impurity data for drug master files (DMFs) and investigational new drug (IND) applications.

Basic Information

Product Name	Cefadroxil Sulfoxide
CAS No.	182290-77-3
Molecular Formula	C16H17N3O6S
Molecular Weight	379.39 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-oxide; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, 5-oxide, (6R,7R)-; Cefadroxil S-Oxide; Cefadroxil Sulfoxide Impurity
EINECS	Contact for details

Quality Control

Our Cefadroxil Sulfoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for pharmaceutical R&D and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.