Description

(S)-(-)-1,1,1-Trifluoroundecan-2-Ol CAS NO 181933-95-9 is a high-purity chiral fluorinated alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring a stereogenic center and a terminal trifluoromethyl group, makes it a valuable intermediate for creating compounds with tailored physicochemical and biological properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Research: Used in creating advanced, bioactive molecules for crop protection agents, leveraging the metabolic stability often imparted by the trifluoromethyl group.
• Liquid Crystal & Advanced Material Synthesis: Serves as a precursor for fluorinated mesogens and other specialty materials where specific polarity and steric properties are required.
• Asymmetric Catalysis & Ligand Development: Employed in the preparation of chiral ligands and catalysts for enantioselective synthesis.
• Probe & Diagnostic Agent Development: Utilized in the design of molecular probes and imaging agents, benefiting from the distinct properties of the fluorine atoms.

Basic Information

Product Name	(S)-(-)-1,1,1-Trifluoroundecan-2-Ol
CAS No.	181933-95-9
Molecular Formula	C₁₁H₂₁F₃O
Molecular Weight	226.28 g/mol
Synonyms	(S)-1,1,1-Trifluoroundecan-2-ol; (S)-(-)-1,1,1-Trifluoro-2-undecanol; (2S)-1,1,1-Trifluoroundecan-2-ol; (S)-2-Trifluoromethyl-1-undecanol; (S)-α-(Trifluoromethyl)undecyl alcohol; (S)-1,1,1-Trifluoro-2-hydroxyundecane; (S)-TFU; (S)-Trifluoroundecanol
EINECS	Contact for details

Quality Control

Our (S)-(-)-1,1,1-Trifluoroundecan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98% by GC/HPLC), enantiomeric excess (typically ≥99% ee), and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.