Description

2-(Dicyclohexylphosphinoethyl)Trimethylammonium Chloride is a specialized quaternary ammonium salt featuring a phosphine ligand, making it a valuable precursor for synthesizing air-stable, water-soluble transition metal catalysts. This compound is engineered to bridge the gap between homogeneous catalysis and industrial process requirements, offering enhanced stability and ease of handling. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, fine chemical, and advanced materials sectors for applications in cross-coupling, hydrogenation, and other catalytic transformations.

Application

• Precursor for Water-Soluble Catalysts: Serves as a key ligand source for creating palladium, rhodium, and ruthenium complexes used in aqueous-phase catalytic reactions.
• Pharmaceutical Intermediate Synthesis: Facilitates key cross-coupling steps (e.g., Suzuki, Heck, Sonogashira reactions) in the production of active pharmaceutical ingredients (APIs).
• Homogeneous Catalysis Research: Enables academic and industrial research into new catalytic cycles and reaction mechanisms under milder conditions.
• Fine Chemical Manufacturing: Used in the synthesis of complex organic molecules, agrochemicals, and specialty polymers where high selectivity is required.
• Ligand for Asymmetric Synthesis: Potential building block for developing chiral phosphine ligands for enantioselective catalysis.
• Material Science: Employed in the surface modification of nanoparticles and the creation of catalytic thin films.

Basic Information

Product Name	2-(Dicyclohexylphosphinoethyl)Trimethylammonium Chloride
CAS No.	181864-78-8
Molecular Formula	C₁₇H₃₅ClNP
Molecular Weight	319.89 g/mol
Synonyms	2-(Dicyclohexylphosphino)-N,N,N-trimethylethanaminium Chloride; Trimethyl[2-(dicyclohexylphosphino)ethyl]ammonium Chloride; DCPE-TMA Chloride; Phosphine Quaternary Ammonium Salt; Water-Soluble Phosphine Ligand Precursor; N,N,N-Trimethyl-2-(dicyclohexylphosphino)ethanaminium Chloride; 181864-78-8
EINECS	Contact for details

Quality Control

Our production of 2-(Dicyclohexylphosphinoethyl)Trimethylammonium Chloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.