Description

Propanamide, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is a high-value, protected intermediate used in advanced organic synthesis. This compound is crucial for its role as a building block in the development of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups with high selectivity.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a masked hydroxylamine or amide functionality.
• Peptidomimetic Research: Serves as a building block for constructing novel peptide analogs and protease inhibitors in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Propanamide, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci)
CAS No.	181636-84-0
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	3-(Tetrahydro-2H-pyran-2-yloxy)propanamide; 3-(THP-Oxy)propanamide; 3-(Tetrahydropyran-2-yloxy)propanamide; N-(3-(Tetrahydro-2H-pyran-2-yloxy)propyl)amide; Propanamide, 3-((tetrahydro-2H-pyran-2-yl)oxy)-; THP-Protected 3-Hydroxypropanamide; 181636-84-0; 3-(Oxiran-2-ylmethoxy)propanamide (related structure)
EINECS	Contact for details

Quality Control

Our Propanamide, 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.