Description

7-Amino-1,2,3,4-2-Trifluoroacetyltetrahydroisoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoroacetylated isoquinoline structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	7-Amino-1,2,3,4-2-Trifluoroacetyltetrahydroisoquinoline
CAS No.	181634-14-0
Molecular Formula	C11H11F3N2O
Molecular Weight	244.21 g/mol
Synonyms	1,2,3,4-Tetrahydro-7-isoquinolinamine, 2-(trifluoroacetyl)-; 2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinamine; 7-Amino-2-trifluoroacetyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-(trifluoroacetyl)-7-isoquinolinamine; 7-Amino-2-trifluoroacetyltetrahydroisoquinoline; 7-Amino-1,2,3,4-tetrahydro-2-(trifluoroacetyl)isoquinoline
EINECS	Contact for details

Quality Control

Our 7-Amino-1,2,3,4-2-Trifluoroacetyltetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.