Description

Bis(3,5-Di-tert-Butylphenyl)Chlorophosphine is a specialized organophosphorus compound widely used as a key ligand precursor and intermediate in advanced chemical synthesis. Its sterically hindered structure makes it particularly valuable for creating highly active and selective catalysts, especially in cross-coupling reactions and polymerization processes. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over catalytic systems.

Application

• Catalyst Ligand Synthesis: A crucial precursor for the preparation of bulky, electron-rich phosphine ligands used in homogeneous catalysis.
• Pharmaceutical Intermediates: Employed in the synthesis of complex drug molecules, particularly where palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) are required.
• Agrochemical Manufacturing: Used in the development of novel active ingredients and performance chemicals that rely on tailored catalytic processes.
• Polymerization Catalysts: Serves as a ligand component in catalysts for olefin polymerization and other advanced polymer syntheses.
• Material Science Research: Applied in the development of new organometallic complexes and functional materials.
• Fine Chemical Production: Acts as a building block for other specialty phosphines and phosphorus-containing compounds.

Basic Information

Product Name	Bis(3,5-Di-tert-Butylphenyl)Chlorophosphine
CAS No.	181257-36-3
Molecular Formula	C28H42ClP
Molecular Weight	445.06 g/mol
Synonyms	Chlorobis(3,5-di-tert-butylphenyl)phosphine; (3,5-Di-tert-butylphenyl)chlorophosphine (dimer-related); Bis(3,5-bis(1,1-dimethylethyl)phenyl)chlorophosphine; Chloro-bis(3,5-di-tert-butylphenyl)phosphane; Phosphinous chloride, P,P-bis[3,5-bis(1,1-dimethylethyl)phenyl]-; Ligand Precursor L1 (common research alias); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Bis(3,5-Di-tert-Butylphenyl)Chlorophosphine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by NMR or HPLC), chloride content, and moisture level is provided with every shipment. We support cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container sealed when not in use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (NMR/HPLC)	≥ 97.0%
Chloride Content	Conforms
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.