Description

Leptin, Mouse is a recombinant protein hormone that plays a critical role in regulating energy balance and metabolism. This high-purity product is essential for life science research, enabling the study of appetite control, obesity, diabetes, and metabolic signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in metabolic disease research and therapeutic development.

Application

• Metabolic Research: Fundamental studies on energy homeostasis, appetite regulation, and adipose tissue biology.
• Drug Discovery & Development: Screening and validation of compounds targeting leptin signaling pathways for obesity and metabolic disorders.
• Cell-Based Assays: Used as a critical reagent in in vitro models to study receptor binding, signal transduction (JAK-STAT pathway), and cellular responses.
• Biomarker Studies: Investigation of leptin resistance and its correlation with various disease states.
• Antibody Production & Validation: Serving as an immunogen for generating specific antibodies or as a standard in immunoassays (ELISA, RIA).
• Preclinical Animal Studies: Administration in mouse models to evaluate therapeutic effects on metabolism and related conditions.

Basic Information

Product Name	Leptin, Mouse
CAS No.	181030-10-4
Molecular Formula	C750H1186N208O224S8 (Approximate, for full-length protein)
Molecular Weight	~16 kDa
Synonyms	Mouse Leptin; Recombinant Mouse Leptin; Leptin (mouse); Obese Protein (mouse); OB Protein; LEP (mouse); Leptin, murine; Leptin protein, mouse; 16 kDa protein leptin
EINECS	Contact for details

Quality Control

Our Leptin, Mouse is produced under stringent conditions and undergoes comprehensive analytical testing to ensure high purity, biological activity, and batch-to-batch consistency. Quality is verified by multiple orthogonal methods including SDS-PAGE, HPLC, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, endotoxin levels, biological activity (via cell-based assay), and identity is provided with each batch to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Mass Spec)	Consistent with molecular weight
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Biological Activity	Determined by cell-based proliferation/activation assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.