Description

4-(4-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile is a versatile and high-value pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its unique piperidine and benzonitrile functional groups. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its nitrile functionality.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process chemistry optimization.
• Ligand and Catalyst Precursor: Potential use in creating specialized ligands for catalytic systems in fine chemical manufacturing.
• Custom Synthesis Projects: Supplied to contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) for bespoke chemical production.

Basic Information

Product Name	4-(4-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile
CAS No.	180847-37-4
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	1-[(4-Cyanophenyl)methyl]-4-piperidinemethanol; 4-[(4-Hydroxymethylpiperidin-1-yl)methyl]benzonitrile; 4-(Hydroxymethyl)-1-[(4-cyanobenzyl)]piperidine; 1-(4-Cyanobenzyl)-4-piperidinemethanol; 4-(1-Piperidinylmethyl)benzonitrile-4-methanol derivative; 4-(Piperidin-1-ylmethyl)benzonitrile-4-methanol; 4-Cyano-α-(4-hydroxymethyl-1-piperidinyl)-p-xylene
EINECS	Contact for details

Quality Control

Our 4-(4-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.