Description

3-Fluoropropyl Trifluoromethanesulfonate is a high-purity fluorinated building block and alkylating agent of significant importance in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 3-fluoropropyl group into complex molecular architectures, enabling the development of novel compounds with tailored properties. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs, where the fluorine atom can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced fluorinated pesticides and herbicides, leveraging fluorine's ability to improve lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a critical building block for creating fluorinated liquid crystal compounds used in high-performance displays.
• Polymer & Material Science: Employed in the synthesis of specialty fluoropolymers and surface-modifying agents that require specific fluorinated side chains.
• Radioactive Tracer Precursor: Acts as a precursor in the synthesis of compounds labeled with fluorine-18 (18F) for Positron Emission Tomography (PET) imaging.
• Organic Synthesis & Methodology: A versatile alkylating agent in academic and industrial research for constructing C-C and C-O bonds under mild conditions.

Basic Information

Product Name	3-Fluoropropyl Trifluoromethanesulfonate
CAS No.	180597-96-0
Molecular Formula	C4H6F4O3S
Molecular Weight	210.15 g/mol
Synonyms	1-Fluoro-3-(trifluoromethanesulfonyloxy)propane; 3-Fluoropropyl Triflate; 3-Fluoropropanol Triflate; 3-Fluoropropyl Trifluoromethanesulphonate; Trifluoromethanesulfonic Acid 3-Fluoropropyl Ester; 3-FPTf; 3-Fluoropropyl OTf; Propane, 1-fluoro-3-[(trifluoromethyl)sulfonyl]oxy]-
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoropropyl Trifluoromethanesulfonate is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and Karl Fischer titration to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.