Description

Acetamide, 2,2,2-Trifluoro-n-(3-Iodophenyl)- is a specialized halogenated acetamide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both trifluoromethyl and iodoaryl substituents, makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Building block for advanced polymers and liquid crystals, where the iodine atom allows for further functionalization via cross-coupling reactions.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of molecular imaging agents.
• Organic Synthesis: Versatile reagent for introducing the 2,2,2-trifluoro-N-(3-iodophenyl)acetamide moiety into complex molecular architectures via palladium-catalyzed couplings.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-(3-Iodophenyl)-
CAS No.	180530-11-4
Molecular Formula	C8H5F3INO
Molecular Weight	315.03 g/mol
Synonyms	2,2,2-Trifluoro-N-(3-iodophenyl)acetamide; N-(3-Iodophenyl)-2,2,2-trifluoroacetamide; 3'-Iodo-2,2,2-trifluoroacetanilide; α,α,α-Trifluoro-3'-iodoacetanilide; 2,2,2-Trifluoroacet-3'-iodoanilide; TFIA; TFA-3-Iodoaniline derivative
EINECS	Contact for details

Quality Control

Our production of Acetamide, 2,2,2-Trifluoro-n-(3-Iodophenyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and scale-up activities under cGMP-like standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.