Description

3-Amino-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid is a specialized fluorinated amino acid derivative that serves as a high-value building block in advanced organic synthesis. Its unique structure, featuring both an amino acid backbone and a trifluoromethylphenyl group, makes it a critical intermediate for creating compounds with enhanced biological activity and metabolic stability. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides where the trifluoromethyl group can improve efficacy and environmental profile.
• Peptidomimetics & Bioactive Molecules: Incorporated into peptide analogs to enhance stability, bioavailability, and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for creating specialty polymers with unique surface properties or optical characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes.

Basic Information

Product Name	3-Amino-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid
CAS No.	180263-44-9
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid; β-Amino-β-(4-trifluoromethylphenyl)propionic acid; (R/S)-3-Amino-3-(4-trifluoromethylphenyl)propionic acid; 4-(Trifluoromethyl)-β-phenyl-β-alanine; 3-Amino-3-(4-trifluoromethylphenyl)propanoic acid; 180263-44-9; ATFMPA
EINECS	Contact for details

Quality Control

Our production of 3-Amino-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP manufacturing standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.