Description

n-[[4-(Trifluoromethyl)Phenyl]Methyl]-Formamide is a specialized organic compound featuring a formamide group linked to a trifluoromethylphenyl moiety. This structure is of significant value in advanced organic synthesis, particularly as a key intermediate for constructing complex molecules with enhanced biological activity and physicochemical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modification: Employed to introduce fluorinated aromatic units into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: Acts as a formylating agent or a protected amine precursor in multi-step synthetic routes for complex heterocycles and fine chemicals.

Basic Information

Product Name	n-[[4-(Trifluoromethyl)Phenyl]Methyl]-Formamide
CAS No.	180207-85-6
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	N-[[4-(Trifluoromethyl)phenyl]methyl]formamide; 4-(Trifluoromethyl)benzylformamide; N-[(4-Trifluoromethylphenyl)methyl]formamide; α-(Trifluoromethyl)benzylformamide; Formamide, N-[[4-(trifluoromethyl)phenyl]methyl]-; 1-(4-Trifluoromethylphenyl)-N-formylmethanamine; (4-Trifluoromethylbenzyl)formamide
EINECS	Contact for details

Quality Control

Our n-[[4-(Trifluoromethyl)Phenyl]Methyl]-Formamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.