Description

1-(Bromomethyl)-3-Nitro-5-(Trifluoromethyl)Benzene is a versatile and high-value aromatic building block characterized by its bromomethyl, nitro, and trifluoromethyl functional groups. This compound is essential for advanced organic synthesis, enabling the introduction of multiple reactive handles for constructing complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with unique electronic or surface properties.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its distinct substitution pattern.
• Fluorine Chemistry: A valuable substrate for further functionalization in fluorine chemistry, exploring the effects of the CF3 group on reactivity and physical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	1-(Bromomethyl)-3-Nitro-5-(Trifluoromethyl)Benzene
CAS No.	180146-67-2
Molecular Formula	C9H5BrF3NO2
Molecular Weight	296.04 g/mol
Synonyms	3-Nitro-5-(trifluoromethyl)benzyl bromide; α-Bromo-3-nitro-5-(trifluoromethyl)toluene; 5-(Bromomethyl)-1-nitro-3-(trifluoromethyl)benzene; 3-(Bromomethyl)-5-nitrobenzotrifluoride; 1-Bromomethyl-3-nitro-5-trifluoromethylbenzene; Benzene, 1-(bromomethyl)-3-nitro-5-(trifluoromethyl)-; 3-Nitro-α-bromo-5-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Every batch of 1-(Bromomethyl)-3-Nitro-5-(Trifluoromethyl)Benzene is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.