Description

1-Methoxy-2-Methyl-3,5-Bis(Trifluoromethyl)Benzene is a high-value, multi-fluorinated aromatic building block designed for advanced chemical synthesis. Its unique structure, featuring methoxy and trifluoromethyl groups, provides exceptional electronic and steric properties critical for developing novel materials and active compounds. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorinated motifs for enhanced performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl groups improve lipophilicity, metabolic stability, and biological activity.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing charge transport and thermal stability.
• Catalyst & Ligand Development: Employed in the design of novel organometallic catalysts and ligands for asymmetric synthesis and cross-coupling reactions.
• Polymer & Resin Modifier: Incorporated into high-performance polymers and resins to impart fluorine-related properties such as chemical resistance, low surface energy, and improved weatherability.
• Chemical Research & Development: A versatile reagent for exploratory organic synthesis in academic and industrial laboratories focused on fluorochemistry.

Basic Information

Product Name	1-Methoxy-2-Methyl-3,5-Bis(Trifluoromethyl)Benzene
CAS No.	180134-13-8
Molecular Formula	C11H8F6O
Molecular Weight	270.17 g/mol
Synonyms	2-Methyl-1-methoxy-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)-2-methylanisole; 1-Methoxy-2-methyl-3,5-di(trifluoromethyl)benzene; 2-Methyl-3,5-bis(trifluoromethyl)anisole; 3,5-Di(trifluoromethyl)-2-methylanisole; 2-Methyl-1-methoxy-3,5-di(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)-o-methylanisole
EINECS	Contact for details

Quality Control

Every batch of 1-Methoxy-2-Methyl-3,5-Bis(Trifluoromethyl)Benzene is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flame. Due to its highly volatile nature and classification as a fluoride/strong alkali, it should be kept separate from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.40 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.