Description

[2-(3-Amino-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative primarily used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development, where it serves as a key intermediate. It is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular disorders.
• Peptide Mimetics & PROTACs: Used in the construction of peptide-like structures and Proteolysis Targeting Chimeras (PROTACs) due to its protected amine functionality.
• Agrochemical Synthesis: Serves as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Dye & Pigment Chemistry: Acts as a precursor in the synthesis of advanced organic dyes and functional pigments.
• Polymer Modification: Used to introduce amine functionality into polymer backbones for creating specialty polymers with tailored properties.
• Bioconjugation Chemistry: The protected amine group is valuable for creating linkers in antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Product Name	[2-(3-Amino-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	180079-94-1
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	tert-Butyl N-[2-(3-aminophenyl)ethyl]carbamate; 3-[2-[(tert-Butoxycarbonyl)amino]ethyl]aniline; N-Boc-3-(2-aminoethyl)aniline; Boc-Dal-OH(Bzl); (3-Aminophenyl)ethylcarbamic Acid tert-Butyl Ester; 1-(3-Aminophenyl)-2-[(tert-butoxycarbonyl)amino]ethane; N-(2-(3-Aminophenyl)ethyl)carbamic Acid tert-Butyl Ester; BOC-3-A-Phe-OH
EINECS	Contact for details

Quality Control

Our [2-(3-Amino-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance as a synthesis intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.