Description

Ethanone, 1-[4-(Difluoromethyl)Phenyl]- (9Ci) is a specialized organic building block featuring a difluoromethylphenyl moiety attached to an ethanone (acetyl) group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Studies: An important compound for investigating the effects of fluorine substitution on molecular reactivity and physicochemical properties in academic and industrial R&D.

Basic Information

Product Name	Ethanone, 1-[4-(Difluoromethyl)Phenyl]- (9Ci)
CAS No.	179990-93-3
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-[4-(Difluoromethyl)phenyl]ethanone; 4'-Difluoromethylacetophenone; 4-(Difluoromethyl)acetophenone; p-Difluoromethylacetophenone; 4-Acetylbenzyl Difluoride; (4-Difluoromethylphenyl)methyl ketone; α,α-Difluoro-4-methylacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[4-(Difluoromethyl)Phenyl]- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.