Description

Naphthalene, 2-Fluoro-1,2,3,4-Tetrahydro-1-Methylene- (9Ci) CAS NO 179990-74-0 is a specialized fluorinated tetrahydro-naphthalene derivative, serving as a valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which is engineered to introduce both fluorine and a reactive methylene group into complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Acts as a precursor for developing specialty polymers and advanced organic materials with specific electronic or optical properties.
• Fluorine Chemistry: A versatile reagent for introducing fluorine into complex organic frameworks, enabling structure-activity relationship (SAR) studies.
• Academic & R&D: Serves as a critical substrate for methodological development in organic synthesis, including catalysis and new bond-forming reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fine chemicals and other specialty intermediates.

Basic Information

Product Name	Naphthalene, 2-Fluoro-1,2,3,4-Tetrahydro-1-Methylene- (9Ci)
CAS No.	179990-74-0
Molecular Formula	C11H11F
Molecular Weight	162.20 g/mol
Synonyms	2-Fluoro-1-methylene-1,2,3,4-tetrahydronaphthalene; 1-Methylene-2-fluoro-1,2,3,4-tetrahydronaphthalene; 2-Fluoro-1-methylidene-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydro-2-fluoro-1-methylenenaphthalene; Fluorinated Tetrahydronaphthalene Derivative; 179990-74-0; (9CI) Naphthalene, 2-fluoro-1,2,3,4-tetrahydro-1-methylene-
EINECS	Contact for details

Quality Control

Our Naphthalene, 2-Fluoro-1,2,3,4-Tetrahydro-1-Methylene- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.