Description

2-Fluoro-6-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its unique phenylacetic acid core substituted with fluorine and trifluoromethyl groups. This compound is critical for introducing lipophilicity and metabolic stability into target molecules, making it a sought-after intermediate in advanced synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to create complex, fluorinated organic molecules.
• Material Science Research: Investigated for use in the development of specialty polymers and advanced materials with specific electronic or surface properties.

Basic Information

Product Name	2-Fluoro-6-(Trifluoromethyl)Phenylacetic Acid
CAS No.	179946-32-8
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	2-Fluoro-α-(trifluoromethyl)phenylacetic Acid; [2-Fluoro-6-(trifluoromethyl)phenyl]acetic Acid; 2-Fluoro-6-(trifluoromethyl)benzeneacetic Acid; α-(2-Fluoro-6-(trifluoromethyl)phenyl)acetic Acid; 179946-32-8; 2-Fluoro-6-trifluoromethylphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.