Description

4-Fluoro-2-Methoxyphenylboronic Acid is a versatile and high-purity organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated units can tune electronic properties.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	4-Fluoro-2-Methoxyphenylboronic Acid
CAS No.	179899-07-1
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(4-Fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-4-fluorophenylboronic acid; 4-Fluoro-2-methoxybenzeneboronic acid; 4-Fluoro-o-anisylboronic acid; 4-Fluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(4-fluoro-2-methoxyphenyl)-; 179899-07-1
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay	≥95.0% (by titration)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.