Description

5-Fluoro-2-Methoxyphenylboronic Acid is a high-purity organoboron compound, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides with specific activity profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting biological analytes.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences and specialty chemicals markets.

Basic Information

Product Name	5-Fluoro-2-Methoxyphenylboronic Acid
CAS No.	179897-94-0
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(5-Fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-5-fluorophenylboronic acid; 5-Fluoro-2-methoxybenzeneboronic acid; 5-Fluoro-o-anisylboronic acid; Boronic acid, B-(5-fluoro-2-methoxyphenyl)-; 179897-94-0; 5-Fluoro-2-methoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.