Description

Biotinyl-5-Aminopentanoyl-Antennapedia Homeobox (43-58) Amide is a biotinylated, cell-penetrating peptide (CPP) derivative of the Antennapedia homeodomain sequence, designed for advanced life science research. This compound is engineered to facilitate the intracellular delivery of biotin or biotin-tagged molecules, enabling powerful applications in protein-protein interaction studies, intracellular targeting, and signal transduction analysis. It is an essential tool for researchers in molecular biology, neurobiology, and drug discovery who require precise mechanisms for cargo delivery across cell membranes.

Application

• Intracellular Delivery Vector: Serves as a carrier for transporting biotinylated probes, drugs, or other molecules into living cells for functional studies.
• Protein Localization & Interaction Studies: Used to study intracellular protein trafficking, localization, and protein-protein interactions via biotin-streptavidin detection systems.
• Signal Transduction Research: Facilitates the investigation of intracellular signaling pathways by delivering modulators or inhibitors to specific cellular compartments.
• Neuroscience Research: Applied in studies of neuronal development, function, and repair due to the neurogenic properties of the Antennapedia homeodomain.
• Drug Discovery Platform: Acts as a component in developing novel therapeutic delivery systems for hard-to-transfect cells.
• Diagnostic Probe Development: Utilized in the design of advanced diagnostic assays for detecting intracellular targets.

Basic Information

Product Name	Biotinyl-5-Aminopentanoyl-Antennapedia Homeobox (43-58) Amide
CAS No.	179764-32-0
Molecular Formula	C96H155N31O22S
Molecular Weight	2115.5 g/mol
Synonyms	Biotin-Ahx-Antp (43-58); Biotinyl-6-aminohexanoyl-Antennapedia (43-58) amide; Antp Homeodomain (43-58) Biotin conjugate; Penetratin (43-58) Biotinylated; Biotin-Ahx-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2; pAntp (43-58)-Biotin; Cell-Penetrating Peptide pAntp Biotin Labeled
EINECS	Contact for details

Quality Control

Our Biotinyl-5-Aminopentanoyl-Antennapedia Homeobox (43-58) Amide is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for critical research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to quality management principles aligned with ISO standards to guarantee reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water, DMSO, or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.