Description

2,3-Dibromo-1,4-Difluorobenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine and bromine atoms is crucial for modulating biological activity and material properties. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the difluoro-dibromo substitution pattern can enhance efficacy and environmental profile.
• Liquid Crystal Materials: Acts as a core intermediate for creating fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of monomers and precursors for organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in selective fluorination and functional group transformations.

Basic Information

Product Name	2,3-Dibromo-1,4-Difluorobenzene
CAS No.	179737-33-8
Molecular Formula	C6H2Br2F2
Molecular Weight	271.88 g/mol
Synonyms	1,4-Difluoro-2,3-dibromobenzene; 2,3-Dibromo-1,4-difluorobenzene; Benzene, 1,4-difluoro-2,3-dibromo-; 2,3-Dibrom-1,4-difluorbenzol (German); 179737-33-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2,3-Dibromo-1,4-Difluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.