Description

4-(2S)-2-Oxiranylbenzonitrile is a high-purity chiral epoxide building block of significant importance in advanced organic synthesis. Its value lies in its stereochemically defined oxirane ring and nitrile functionality, which enable precise and efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of biologically active molecules and potential drug candidates.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds via ring-opening reactions of the epoxide moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals requiring high stereochemical fidelity.
• Agrochemical Research: Utilized in the development of new chiral active ingredients for crop protection.
• Material Science: A building block for advanced polymers and functional materials with specific optical properties.

Basic Information

Product Name	4-(2S)-2-Oxiranylbenzonitrile
CAS No.	179694-33-8
Molecular Formula	C9H7NO
Molecular Weight	145.16 g/mol
Synonyms	(S)-4-(Oxiran-2-yl)benzonitrile; (2S)-2-(4-Cyanophenyl)oxirane; 4-[(2S)-Oxiranyl]benzonitrile; (S)-2-(4-Cyanophenyl)oxirane; (S)-4-(2-Oxiranyl)benzonitrile; 4-((S)-Oxiran-2-yl)benzonitrile; Benzonitrile, 4-[(2S)-2-oxiranyl]-; (S)-Glycidyl benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(2S)-2-Oxiranylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including chiral HPLC, NMR, and GC/MS. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.