Description

2-Amino-2-(2,3-Dihydro-1H-Inden-1-Yl)Acetic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a rigid indane scaffold. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with enhanced conformational stability and biological activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in peptide mimetics and enzyme inhibitor design. The CAS number for this compound is 179185-78-5.

Application

This specialized amino acid derivative serves as a critical intermediate in advanced organic synthesis. Key application areas include:

• Pharmaceutical Intermediates: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Peptidomimetics: Used to construct constrained peptide analogs, improving metabolic stability and receptor selectivity in therapeutic peptides.
• Agrochemical Synthesis: Employed in the research and development of new herbicides and pesticides with unique modes of action.
• Chemical Biology Probes: Useful for creating labeled compounds and activity-based probes to study enzyme function and biological pathways.
• Catalyst and Ligand Development: The indane backbone can be incorporated into chiral ligands for asymmetric catalysis.
• Academic & Institutional Research: Serves as a valuable tool for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Item	Details
Product Name	2-Amino-2-(2,3-Dihydro-1H-Inden-1-Yl)Acetic Acid
CAS No.	179185-78-5
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	1-Indan-1-ylglycine; (1-Indanyl)glycine; 2-Amino-2-(2,3-dihydro-1H-inden-1-yl)acetic acid; 2-Amino(1-indanyl)acetic acid; α-Amino-1-indanacetic acid; (1-Indanyl)aminoacetic acid; 179185-78-5 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2,3-Dihydro-1H-Inden-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.