Description

4-Bromo-3,4,5-trifluoro-1,1-biphenyl is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of halogen and fluorine atoms, which enables precise structural modifications for developing novel materials and active compounds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and liquid crystal material sectors seeking to incorporate unique electronic and steric properties into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine and bromine substituents contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a core structure in the production of fluorinated liquid crystals for high-performance displays (LCDs), offering desirable dielectric anisotropy and viscosity properties.
• Organic Electronic Materials: Acts as a precursor for organic semiconductors, charge-transport materials, and other components used in OLEDs and photovoltaic devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom, facilitating the construction of complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel fluorinated aromatic compounds.

Basic Information

Product Name	4-Bromo-3,4,5-trifluoro-1,1-biphenyl
CAS No.	178820-38-7
Molecular Formula	C12H6BrF3
Molecular Weight	287.08 g/mol
Synonyms	4-Bromo-3,4,5-trifluorobiphenyl; [1,1'-Biphenyl]-4-bromo-3,4,5-trifluoro; 3,4,5-Trifluoro-4-bromobiphenyl; 4-Bromo-3,4,5-trifluoro-1,1'-biphenyl; 4-Bromo-3,4',5-trifluorobiphenyl; 4-Bromo-3,4,5-trifluorodiphenyl; 1-Bromo-2,3,4-trifluoro-4-phenylbenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,4,5-trifluoro-1,1-biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.