Description

4-Trifluoromethylphenethyliodide CAS NO 178685-14-8 is a high-purity organoiodine compound featuring a phenethyl backbone with a trifluoromethyl substituent. This specialized chemical serves as a critical building block in advanced organic synthesis, enabling the introduction of the valuable trifluoromethylphenethyl moiety into target molecules. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where its unique structure imparts desirable metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials requiring specific aromatic and aliphatic linkages.
• Cross-Coupling Reactions: Acts as an efficient electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) for C-C bond formation.
• Fluorine-Containing Compound Library Synthesis: Critical for medicinal chemistry and drug discovery programs focused on expanding fluorinated chemical space.
• Advanced Polymer Monomer: Employed in the synthesis of specialty polymers with enhanced chemical resistance and tailored physical properties.

Basic Information

Product Name	4-Trifluoromethylphenethyliodide
CAS No.	178685-14-8
Molecular Formula	C9H8F3I
Molecular Weight	300.06 g/mol
Synonyms	1-(2-Iodoethyl)-4-(trifluoromethyl)benzene; 2-(4-Trifluoromethylphenyl)ethyl Iodide; 4-(Trifluoromethyl)phenethyl Iodide; 2-(4-(Trifluoromethyl)phenyl)ethyliodide; α,α,α-Trifluoro-2-iodoethylbenzene-p-xylene; (4-Trifluoromethylphenyl)ethyl Iodide; p-Trifluoromethylphenethyliodide
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethylphenethyliodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.