Description

Acetyl-Amylin (8-37) (Human) is a synthetic peptide fragment of the human amylin hormone, specifically the 8-37 sequence with an N-terminal acetylation. This compound serves as a potent and selective antagonist of the amylin receptor, making it a critical research tool for studying metabolic pathways, insulin secretion, and diabetes. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on endocrinology and metabolic disease. The product is supplied to the highest purity standards to ensure reliable and reproducible experimental results.

Application

• Pharmacological Research: Used as a reference standard and antagonist in studies of amylin's role in glucose metabolism and satiety signaling.
• Drug Discovery & Development: A key biochemical tool for screening and validating potential therapeutics for type 2 diabetes and obesity.
• Academic & Biomedical Research: Employed in university and institutional labs for fundamental research into hormone-receptor interactions and peptide biology.
• Biotechnology Reagent: Utilized in assay development, cell-based studies, and receptor characterization within biotech companies.
• In Vitro Diagnostics (IVD) Development: May serve as a critical component in developing diagnostic assays for metabolic disorders.

Basic Information

Product Name	Acetyl-Amylin (8-37) (Human)
CAS No.	178603-79-7
Molecular Formula	C142H231N41O43S2
Molecular Weight	3132.7 g/mol
Synonyms	Acetyl-Amylin (8-37); Ac-hAmylin(8-37); hAmylin(8-37) acetate; Amylin Receptor Antagonist (8-37); IAPP(8-37), N-acetyl-; Islet Amyloid Polypeptide Fragment (8-37); DACRA (Dual Amylin and Calcitonin Receptor Agonist) research analogue; N-Acetyl-Islet Amyloid Polypeptide (8-37)
EINECS	Contact for details

Quality Control

Our Acetyl-Amylin (8-37) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.