Description

5-(4-(Trifluoromethyl)Phenyl)-4H-1,2,4-Triazol-3-Amine is a high-value, functionalized heterocyclic compound featuring a trifluoromethylphenyl group, a key structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the synthesis of novel active ingredients with enhanced metabolic stability and bioavailability. It is essential for R&D and production teams in the life sciences and specialty chemical sectors seeking to develop new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Building Block: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Synthesis: Employed in organic synthesis as a versatile amine-containing scaffold for constructing complex molecular architectures via coupling and cyclization reactions.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	5-(4-(Trifluoromethyl)Phenyl)-4H-1,2,4-Triazol-3-Amine
CAS No.	178556-79-1
Molecular Formula	C9H7F3N4
Molecular Weight	228.18 g/mol
Synonyms	3-Amino-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazole; 5-[4-(Trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-amine; 4H-1,2,4-Triazol-3-amine, 5-[4-(trifluoromethyl)phenyl]-; 5-(4-Trifluoromethylphenyl)-1,2,4-triazol-3-ylamine; 5-(alpha,alpha,α-Trifluoro-p-tolyl)-4H-1,2,4-triazol-3-amine
EINECS	Contact for details

Quality Control

Our production of 5-(4-(Trifluoromethyl)Phenyl)-4H-1,2,4-Triazol-3-Amine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.