Description

2(1H)-Naphthalenone, 1-Fluoro-3,4-Dihydro- is a specialized fluorinated naphthalenone derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which incorporates a fluorine atom to modulate electronic properties and enhance reactivity for targeted synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can improve biological activity and environmental stability.
• Material Science: Serves as a precursor for advanced organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Fluorination Chemistry Studies: An important substrate for studying fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Ligand and Catalyst Development: Utilized in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists in both university laboratories and corporate R&D centers exploring new chemical spaces.

Basic Information

Product Name	2(1H)-Naphthalenone, 1-Fluoro-3,4-Dihydro-
CAS No.	178484-16-7
Molecular Formula	C₁₀H₇FO
Molecular Weight	162.16 g/mol
Synonyms	1-Fluoro-3,4-dihydro-2(1H)-naphthalenone; 1-Fluoro-3,4-dihydronaphthalen-2(1H)-one; 1-Fluoro-1,2,3,4-tetrahydronaphthalen-2-one; 1-Fluoro-α-tetralone; Fluorinated α-tetralone; 2-Naphthalenone, 1-fluoro-3,4-dihydro-; 1-Fluoro-3,4-dihydro-2-naphthalenone
EINECS	Contact for details

Quality Control

Our 2(1H)-Naphthalenone, 1-Fluoro-3,4-Dihydro- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.