Description

n-[6-[Bis(4-Methoxyphenyl)Phenylmethoxy]Hexyl]-2,2,2-Trifluoro-Acetamide is a specialized trifluoroacetamide derivative featuring a trityl-protected hexylamine linker. This compound matters as a high-purity, protected intermediate critical for advanced organic synthesis and pharmaceutical research, enabling the controlled introduction of amine functionalities. It is primarily needed by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly where a protected amine linker is required.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) as a reagent for introducing modified amino acid residues or as a protecting group strategy.
• Agrochemical Research: Acts as a precursor in the development of new pesticides and herbicides with enhanced stability and efficacy.
• Bioconjugation: Utilized in the preparation of chemical probes, antibody-drug conjugates (ADCs), and other bioconjugates due to its reactive trifluoroacetamide group and cleavable linker.
• Material Science: Employed in the synthesis of functional polymers and dendrimers that require specific, protected amine sites for further modification.
• Chemical Biology Tool: Functions as a reagent for labeling or modifying biomolecules in proteomics and diagnostic assay development.

Basic Information

Product Name	n-[6-[Bis(4-Methoxyphenyl)Phenylmethoxy]Hexyl]-2,2,2-Trifluoro-Acetamide
CAS No.	178261-42-2
Molecular Formula	C35H38F3NO4
Molecular Weight	593.68 g/mol
Synonyms	N-[6-[Bis(4-methoxyphenyl)phenylmethoxy]hexyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[6-[[bis(4-methoxyphenyl)phenylmethoxy]hexyl]acetamide; Trityl-protected Hexylamine Trifluoroacetamide; MMTr-(CH2)6-NHTFA; 4,4'-Dimethoxytritylhexylamine Trifluoroacetamide; DMT-Hexylamine-TFA; N-(6-((Bis(4-methoxyphenyl)(phenyl)methoxy)hexyl)-2,2,2-trifluoroacetamide
EINECS	Contact for details

Quality Control

Our n-[6-[Bis(4-Methoxyphenyl)Phenylmethoxy]Hexyl]-2,2,2-Trifluoro-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.