Description

Nalpha-(5-Fluoro-2,4-Dinitrophenyl)-L-Leucinamide is a specialized, high-purity chemical building block designed for advanced research and development. This compound is critical for applications requiring precise molecular architecture, particularly in the synthesis of complex peptides and modified amino acid derivatives. It serves as a key intermediate for pharmaceutical researchers, medicinal chemists, and biochemists focused on developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of targeted molecular probes.
• Bioconjugation & Labeling: Serves as a reactive handle for the site-specific modification of peptides, proteins, and other biomolecules.
• Proteomics & Biochemistry: Employed in the study of enzyme-substrate interactions and the design of enzyme inhibitors.
• Chemical Biology Tool Development: Utilized to create affinity tags, fluorescent probes, and other research reagents.
• Academic & Industrial R&D: A valuable reagent for exploratory synthesis in both university laboratories and corporate R&D centers.

Basic Information

Product Name	Nalpha-(5-Fluoro-2,4-Dinitrophenyl)-L-Leucinamide
CAS No.	178065-29-7
Molecular Formula	C₁₂H₁₅FN₄O₅
Molecular Weight	314.27 g/mol
Synonyms	Nα-(5-Fluoro-2,4-dinitrophenyl)-L-leucinamide; L-Leucinamide, N-[5-fluoro-2,4-dinitrophenyl]-; 5-Fluoro-2,4-dinitrophenyl-L-leucinamide; N-(5-Fluoro-2,4-dinitrophenyl)leucinamide; FDNP-Leucinamide; 178065-29-7; N-[(5-Fluoro-2,4-dinitrophenyl)]-L-leucinamide
EINECS	Contact for details

Quality Control

Our Nalpha-(5-Fluoro-2,4-Dinitrophenyl)-L-Leucinamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.