Description

n-(3-Methoxypropyl) L-Z-Valinamide CAS NO 178049-55-3 is a specialized chiral amino acid derivative designed for advanced pharmaceutical synthesis and research. This high-purity building block is critical for constructing complex peptide-based molecules with specific stereochemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Protease Inhibitor Research: Used in the design and development of inhibitors targeting specific proteolytic enzymes.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for creating stable, bioavailable peptidomimetics in drug discovery.
• Chemical Biology Probes: Incorporated into labeled peptides and activity-based probes for studying enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective organic synthesis.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in medicinal chemistry and peptide science.

Basic Information

Product Name	n-(3-Methoxypropyl) L-Z-Valinamide
CAS No.	178049-55-3
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	L-Valinamide, N-(3-methoxypropyl)-; (S)-2-Amino-3-methyl-N-(3-methoxypropyl)butanamide; N-(3-Methoxypropyl)-L-valinamide; Valinamide, N-(3-methoxypropyl)-, L-; Z-Valinamide, N-(3-methoxypropyl)-, L-; (2S)-2-Amino-3-methyl-N-(3-methoxypropyl)butanamide; 178049-55-3; L-Valinamide derivative
EINECS	Contact for details

Quality Control

Our n-(3-Methoxypropyl) L-Z-Valinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.